CDK2 degrader 1 - CAS 3036604-59-5

CDK2 degrader1 (Compound 3) is an orally active cyclin-dependent kinase 2 (CDK2) degrader based on PROTAC technology. It binds to cerebellum, inducing ubiquitination of CDK2 followed by proteasomal degradation pathway. CDK2 degrader1 is utilized in the research of multiple cancers.

3036604-59-5

C23H27F2N3O4

447.48

N(C(OC[C@H]1[C@]2(C[C@@](C1)(CC2)[H])[H])=O)C3CN(C3)C4=CC(F)=C(C(F)=C4)C5C(=O)NC(=O)CC5

-20°C

Ice Packs

PROTAC