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CDK4/6-IN-14 - CAS 2699091-15-9

CDK4/6-IN-14 - CAS 2699091-15-9

MF-0146444-01

$1,383.80 USD
$1,383.80 USD
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Product Details

  • Bioactivity

    CDK4/6-IN-14 is a potent, highly selective inhibitor of Cyclin-Dependent Kinases 4 and 6 (CDK4/6), with inhibition concentrations (IC50s) of 10 nM and 16 nM, respectively. It shows over 60-fold selectivity for CDK4/6 compared to CDKs 1, 2, 7, and 9, and exhibits significant selectivity against 205 other kinases.

  • Target

    Others, CDK

  • Related Pathways

    Cell Cycle/Checkpoint, Others

  • CAS Number

    2699067

  • Molecular Formula

    C24H27ClFN7O

  • Molecular Weight

    483.97

  • SMILES

    Cl.O=C1C=2C=CC(=CC2CCN1CC)C3=NC(=NC=C3F)NC4=NC=C(C=C4)N5CCNCC5

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound