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CDK4/6-IN-3 - CAS 2366237-37-6

CDK4/6-IN-3 - CAS 2366237-37-6

MF-0004900-01

$3,577.55 USD
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Product Details

  • Bioactivity

    CDK4/6-IN-3, a brain-penetrant CDK4/CDK6 inhibitor (Kis: <0.3 nM and 2.2 nM), is used for the treatment of glioblastoma and inhibits CDK1 with a Ki of 110 nM.

  • Target

    CDK

  • Related Pathways

    Cell Cycle/Checkpoint

  • CAS Number

    2366237-37-6

  • Molecular Formula

    C25H31FN8

  • Molecular Weight

    462.57

  • SMILES

    C(C)N1CC2(CN(C2)C=3C=CC(NC=4N=C(C(F)=CN4)C5=C6N(N=C5)CCCC[C@H]6C)=NC3)C1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound