CDK5-IN-4 - CAS 1212711-91-5

CDK5-IN-4 (compound 4), a potent type-II multikinase inhibitor, targets CDK5 with an IC 50 of 9.8 μM. Additionally, it inhibits GSK-3α, GSK-3β, CDK9, and CDK2, demonstrating IC 50 values of 0.98, 4.00, 1.76, and 6.24 μM, respectively. This compound is applicable in glioblastoma research.

GSK-3, CDK

Cell Cycle/Checkpoint, PI3K/Akt/mTOR signaling, Stem Cells

1212711-91-5

C24H24FN5O3

449.48

N([C@@H]1[C@@]2([C@@]([C@@H](NC(NCC3=CC=CC=C3)=O)CO2)(OC1)[H])[H])C=4N=C(C=CN4)C5=CC(F)=CC=C5

-20°C

Ice Packs

Small Compound