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CDK8/19-IN-1 - CAS 1818427-07-4
CDK8/19-IN-1 - CAS 1818427-07-4
SKU:MF-0004902-01
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$1,515.42 USD
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Product Details
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Bioactivity
CDK8/19-IN-1 is a selective, orally bioavailable dual inhibitor of CDK8 and CDK19, with IC50 values of 0.46 nM for CDK8, 0.99 nM for CDK19, and 270 nM for [CDK9].
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Target
ASK, CDK
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Related Pathways
Cell Cycle/Checkpoint, Apoptosis
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CAS Number
1818427-07-4
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Molecular Formula
C19H18N4O4S2
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Molecular Weight
430.5
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SMILES
O(C1=C2C(=C(C(N)=O)S1)CCC3=C2SN=C3)C=4C=CC(C(NCCOC)=O)=NC4
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound