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Molfinity

CDK8/19-IN-1 - CAS 1818427-07-4

CDK8/19-IN-1 - CAS 1818427-07-4

SKU:MF-0004902-01

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  • Bioactivity

    CDK8/19-IN-1 is a selective, orally bioavailable dual inhibitor of CDK8 and CDK19, with IC50 values of 0.46 nM for CDK8, 0.99 nM for CDK19, and 270 nM for [CDK9].

  • Target

    ASK, CDK

  • Related Pathways

    Cell Cycle/Checkpoint, Apoptosis

  • CAS Number

    1818427-07-4

  • Molecular Formula

    C19H18N4O4S2

  • Molecular Weight

    430.5

  • SMILES

    O(C1=C2C(=C(C(N)=O)S1)CCC3=C2SN=C3)C=4C=CC(C(NCCOC)=O)=NC4

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound