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CDK8/19-IN-2 - CAS 3024381-54-9

CDK8/19-IN-2 - CAS 3024381-54-9

MF-0148017-01

$1,910.30 USD
$1,910.30 USD
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Product Details

  • Bioactivity

    CDK8/19-IN-2 (compound 12) is a potent inhibitor of cyclin-dependent kinases 8 and 19 (CDK8 and CDK19), exhibiting IC 50 values of 2.08 nM and 2.49 nM, respectively. This orally active compound is applicable in the research of acute myeloid leukemia (AML), breast cancer, and lymphoma.

  • Target

    STAT, CDK

  • Related Pathways

    Cell Cycle/Checkpoint, Stem Cells, JAK/STAT signaling

  • CAS Number

    3024381-54-9

  • Molecular Formula

    C17H20Br2F2N4O

  • Molecular Weight

    494.17

  • SMILES

    FC(F)C=1C(Br)=C(Br)C=C2C1N=C(N2C3CCOCC3)N4CCNCC4

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound