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CDK8/19-IN-51 - CAS 1860885-61-5
CDK8/19-IN-51 - CAS 1860885-61-5
SKU:MF-0040260-01
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$515.08 USD
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Product Details
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Bioactivity
CDK8/19-IN-51 is an orally active and highly effective dual inhibitor of CDK8 and CDK19, with anticancer activity. Its IC50 values for CDK8 and CDK19 are 5.1 nM and 5.6 nM, respectively. It is used in studies of colorectal and gastric cancers.
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Target
CDK
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Related Pathways
Cell Cycle/Checkpoint
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CAS Number
1860819
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Purity
>99.99%
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Molecular Formula
C23H22N6O2
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Molecular Weight
414.46
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SMILES
O=C(C1=NC2=C(C=NC(N)=C2C=C1)C3=CC=C(C=C3)C=4C=NN(C4)C)N5CC(OC)C5
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound