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Molfinity

CDK8-IN-11 - CAS 2839338-28-0

CDK8-IN-11 - CAS 2839338-28-0

SKU:MF-0018981-01

Regular price $48.87 USD
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  • Bioactivity

    CDK8-IN-11 is a selective and potent CDK8 inhibitor that shows antiproliferative activity in colon cancer cell lines, inhibiting WNT/β-catenin activation and TCF family transcriptional activity, inducing G1-phase arrest in HCT-116 cells, useful for colon cancer research.

  • Target

    CDK, Wnt/beta-catenin

  • Related Pathways

    Cell Cycle/Checkpoint, Cytoskeletal Signaling, Stem Cells

  • CAS Number

    2839310

  • Purity

    0.9974

  • Molecular Formula

    C19H15F3N4O2

  • Molecular Weight

    388.34

  • SMILES

    O=C(NC1=CC=C(OC2=CN=C(N)C=C2)C=C1)NC3=CC=CC(=C3)C(F)(F)F

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound