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Molfinity

CDK8-IN-13 - CAS 918523-75-8

CDK8-IN-13 - CAS 918523-75-8

SKU:MF-0095292-01

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  • Bioactivity

    CDK8-IN-13 is a CDK8 inhibitor (IC50: 51.9 nM) with potent, selective and oral activity. CDK8-IN-13 induces apoptosis and reduces the expression of p-STAT1 S727 and p-STAT5 S726. CDK8-IN-13 exhibits anti-tumour activity.

  • Target

    Apoptosis, CDK

  • Related Pathways

    Apoptosis, Cell Cycle/Checkpoint

  • CAS Number

    918440

  • Purity

    0.9928

  • Molecular Formula

    C14H11N3O

  • Molecular Weight

    237.26

  • SMILES

    C(N)(=O)C=1C=C(C=2C=C3C(=NC2)NC=C3)C=CC1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound