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CDK8-IN-13 - CAS 918523-75-8
CDK8-IN-13 - CAS 918523-75-8
SKU:MF-0095292-01
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$33.92 USD
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Product Details
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Bioactivity
CDK8-IN-13 is a CDK8 inhibitor (IC50: 51.9 nM) with potent, selective and oral activity. CDK8-IN-13 induces apoptosis and reduces the expression of p-STAT1 S727 and p-STAT5 S726. CDK8-IN-13 exhibits anti-tumour activity.
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Target
Apoptosis, CDK
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Related Pathways
Apoptosis, Cell Cycle/Checkpoint
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CAS Number
918440
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Purity
0.9928
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Molecular Formula
C14H11N3O
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Molecular Weight
237.26
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SMILES
C(N)(=O)C=1C=C(C=2C=C3C(=NC2)NC=C3)C=CC1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound