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Molfinity

CDK8-IN-14 - CAS 2924193-12-2

CDK8-IN-14 - CAS 2924193-12-2

MF-0120437-01

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Product Details

  • Bioactivity

    CDK8-IN-14 (compound 12) effectively inhibits CDK8, demonstrating an IC50 of 39.2 nM, and exhibits potent anti-AML cell proliferation effects, with a GC50 value of 0.02±0.01μM in MOLM-13 cells and 0.03±0.01μM in MV4-11 cells [1].

  • Target

    CDK

  • Related Pathways

    Cell Cycle/Checkpoint

  • CAS Number

    2924193-12-2

  • Molecular Formula

    C18H13N3O2

  • Molecular Weight

    303.31

  • SMILES

    C(N)(=O)C=1C=C(C=2C=C3C(=CNC3=NC2)C=4C=COC4)C=CC1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound