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CDK9-IN-34 - CAS 252725-86-3
CDK9-IN-34 - CAS 252725-86-3
SKU:MF-0142598-01
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$1,383.80 USD
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$1,383.80 USD
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Product Details
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Bioactivity
CDK9-IN-34 (Compound 1b) is an inhibitor of CDK9 with an IC50 of 0.25 μM. It exhibits cytotoxicity against cancer cell lines HCT116, MCF7, and K652, with IC50 values of 1.43 μM, 3.01 μM, and 50.27 μM, respectively. Additionally, CDK9-IN-34 demonstrates antiviral activity against coronavirus 229E with an IC50 of 145.92 μM.
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Target
SARS-CoV, CDK
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Related Pathways
Microbiology/Virology, Cell Cycle/Checkpoint
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CAS Number
252636
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Molecular Formula
C18H20N4
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Molecular Weight
292.38
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SMILES
N=1C=CN2C(=NC(C=3C=CC=CC3)=C2NC4CCCCC4)C1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound