CDK9/PARP-IN-1 - CAS 3032818-67-7

CDK9/PARP-IN-1 (compound 37) is an inhibitor of CDK9 and PARP. It demonstrates IC50 values of 118 nM for CDK9 and 107 nM for PARP1. This compound exhibits a broad-spectrum anti-proliferative effect across various cancer cell lines.

CDK, PARP

Chromatin/Epigenetic, Cell Cycle/Checkpoint, DNA Damage/DNA Repair

3032744

C38H34F2N8O3

688.725

O=C1NN=C(C=2C=CC=CC12)CC3=CC=C(F)C(=C3)C(=O)N4CCN(CC=5C=CN=C(C5)NC6=NC=NC(=C6)C=7C=CC(F)=CC7OCC)CC4

-20°C

Ice Packs

Small Compound