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CDKI-73 - CAS 1421693-22-2

CDKI-73 - CAS 1421693-22-2

MF-0016164-01

$143.63 USD
$143.63 USD
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Product Details

  • Bioactivity

    CDKI-73 is a potent CDK9 inhibitor (Ki: 4 nM) . It shows selective toxicity to CLL cells (LD50=80 nM) versus normal B cell and normal CD34+ cell (LD50>20 uM) .The inhibition of CDK9 induces apoptosis and potentiates the effect of cisplatin.

  • Target

    Apoptosis, CDK

  • Related Pathways

    Cell Cycle/Checkpoint, Apoptosis

  • CAS Number

    1421669

  • Purity

    0.9811

  • Molecular Formula

    C15H15FN6O2S2

  • Molecular Weight

    394.45

  • SMILES

    CNc1nc(C)c(s1)-c1nc(Nc2cccc(c2)S(N)(=O)=O)ncc1F

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound