Molfinity

CE-245677 - CAS 717899-97-3

SKU:MF-0032579-01

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Product Details

Bioactivity
CE-245677 is a potent, reversible inhibitor of Tie2 and TrkA/B kinases, with cellular IC50 values of 4.7 nM and 1 nM, respectively.
Target
Tie-2, Trk receptor
Related Pathways
Tyrosine Kinase/Adaptors
CAS Number
717799
Purity
0.9923
Molecular Formula
C24H22Cl2N6O3
Molecular Weight
513.38
SMILES
COc1ccc(cc1NC(=O)Nc1ccc(Cl)cc1Cl)C(=O)c1cn(C(C)C)c2ncnc(N)c12
Storage Temperature
-20°C
Shipping Conditions
Ice Packs
Category
Small Compound