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Cediranib maleate - CAS 857036-77-2

Cediranib maleate - CAS 857036-77-2

MF-0012059-01

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Product Details

  • Bioactivity

    Cediranib maleate (AZD2171 maleate) is an orally active and highly potent VEGF family receptor tyrosine kinase (VEGFR2) inhibitor that inhibits Flt1, KDR, Flt4, PDGFRα, PDGFRβ, and c-Kit, and up-regulates MHC-I through transcriptional modulation in the study of ovarian cancer.

  • Target

    PDGFR, VEGFR, Autophagy

  • Related Pathways

    Autophagy, Tyrosine Kinase/Adaptors, Angiogenesis

  • CAS Number

    857036-77-2

  • Molecular Formula

    C29H31FN4O7

  • Molecular Weight

    566.58

  • SMILES

    C(=C\C(O)=O)\C(O)=O.O(C=1C2=C(C=C(OCCCN3CCCC3)C(OC)=C2)N=CN1)C=4C(F)=C5C(=CC4)NC(C)=C5

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound