Celecoxib Carboxylic Acid Acyl-β-D-Glucuronide - CAS 264236-79-5

Celecoxib carboxylic acid acyl-β-D-glucuronide is a phase II metabolite of celecoxib . Celecoxib is an anti-inflammatory compound from the diaryl heterocycle class that selectively inhibits cyclooxygenase-2 (COX-2; IC50s = 22.9 and 0.05 μM for COX-1 and COX-2, respectively) . Celecoxib carboxylic acid acyl-β-D-glucuronide is a minor metabolite, accounting for 2% of the administered dose in human urine and rat bile.

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Others

264152

C23H20F3N3O10S

587.48

C(F)(F)(F)C=1C=C(N(N1)C2=CC=C(S(N)(=O)=O)C=C2)C3=CC=C(C(O[C@@H]4O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]4O)=O)C=C3

-20°C

Ice Packs

Small Compound