Cenupatide - CAS 1006388-38-0

Cenupatide is a urokinase plasminogen activator receptor (uPAR) inhibitor. Cenupatide inhibits uPAR binding to the formyl peptide receptors (FPRs) can improve kidney lesions in a rat model of STZ-induced diabetes. Cenupatide reverted STZ-induced up-regulation of uPA levels and activity, while uPAR on podocytes and (s) uPAR were unaffected. In glomeruli, Cenupatide inhibited FPR2 expression.

1006350

C28H47N11O5

617.756

CC(=O)N[C@@H](CCCNC(N)=N)C(=O)NC(C)(C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@](C)(Cc1ccccc1)C(N)=O

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Peptide