CEP-28122 mesylate hydrochloride - CAS 1354545-57-5

CEP-28122 mesylate hydrochloride, a diaminopyrimidine derivative, is a potent, selective, and orally bioavailable ALK inhibitor with an IC50 of 1.9 nM, exhibiting antitumor and good pharmacokinetic activity [1].

ALK

Tyrosine Kinase/Adaptors, Angiogenesis

1354545-57-5

C29H40Cl2N6O6S

671.64

S(C)(=O)(=O)O.N([C@@H]1[C@@]2(C[C@]([C@@H]1C(N)=O)(C=C2)[H])[H])C3=NC(NC=4C(OC)=C5C(=CC4)CC[C@@H](CC5)N6CCOCC6)=NC=C3Cl.Cl

-20°C

Ice Packs

Small Compound