Cephaeline dihydrochloride - CAS 5853-29-2

Cephaeline dihydrochloride is a naturally occurring alkaloid that is a selective CYP2D6 inhibitor with an IC50=121 μM. It has an affinity for and oral activity at the 5-HT4 receptor and is capable of inducing vomiting.

Cytochromes P450, 5-HT Receptor

GPCR/G Protein, Metabolism, Neuroscience

5822

0.9967

C28H40Cl2N2O4

539.53

COC(C=C(CCN1C[C@@H]2CC)C([C@]1([H])C[C@@H]2C[C@@H]3C4=CC(OC)=C(O)C=C4CCN3)=C5)=C5OC.Cl.Cl

-20°C

Ice Packs

Natural Product