Cephalothin sodium - CAS 58-71-9

Cephalothin sodium (Cefalotin) binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. Cephalothin sodium (Cefalotin) is the sodium salt form of cephalothin, a semisynthetic, beta-lactam, the first-generation cephalosporin antibiotic with bactericidal activity. PBPs participate in the terminal stages of assembling the bacterial cell wall, and in reshaping the cell wall during cell division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.

Antibiotic, Antibacterial

Microbiology/Virology

-22

0.9917

C16H15N2NaO6S2

418.4

[Na+].CC(=O)OCC1=C(N2[C@H](SC1)[C@H](NC(=O)Cc1cccs1)C2=O)C([O-])=O

-20°C

Ice Packs

Small Compound