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Ceranib-2 - CAS 1402830-75-4

Ceranib-2 - CAS 1402830-75-4

SKU:MF-0004929-01

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  • Bioactivity

    Ceranib-2 (3-[ (E) -3- (4-hydroxyphenyl) prop-2-enoyl]-4-phenyl-1H-quinolin-2-one) is an inhibitor of ceramidase with an IC50 of 28 μM in SKOV3 cells. Ceranib-2 decreases levels of sphingosine and S1P, induces cell apoptosis and exhibits anticancer activity.

  • Target

    Apoptosis, LPL Receptor, S1P Receptor

  • Related Pathways

    GPCR/G Protein, Apoptosis

  • CAS Number

    1402751

  • Purity

    0.9849

  • Molecular Formula

    C25H19NO3

  • Molecular Weight

    381.42

  • SMILES

    COc1ccc(\C=C\C(=O)c2c(-c3ccccc3)c3ccccc3[nH]c2=O)cc1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound