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Cerberin - CAS 25633-33-4
Cerberin - CAS 25633-33-4
SKU:MF-0124554-01
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Product Details
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Bioactivity
Cerberin is a cardiac glycoside found in C. odollam with cytotoxic and cardiac regulatory properties. It exhibits cytotoxicity against KB and NCI H187 cancer cells (IC50s = 1.92 and 1.24 μg/mL) . Cerberin inhibits Na+/K+-ATPase, elevating intracellular sodium levels and prolonging action potential duration in cardiac cells.
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Target
ATPase
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Related Pathways
Membrane transporter/Ion channel
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CAS Number
25633-33-4
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Molecular Formula
C32H48O9
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Molecular Weight
576.72
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SMILES
O[C@@]12[C@]3([C@@]([C@]4(C)[C@](CC3)(C[C@@H](O[C@H]5[C@@H](OC(C)=O)[C@H](OC)[C@@H](O)[C@H](C)O5)CC4)[H])(CC[C@]1(C)[C@H](CC2)C=6COC(=O)C6)[H])[H]
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Natural Product