Cerdulatinib hydrochloride - CAS 1369761-01-2

Cerdulatinib hydrochloride (PRT2070 hydrochloride) is an oral active, multi-targeted tyrosine kinase inhibitor with IC50 of 12 nM/6 nM/8 nM/0.5 nM and 32 nM for JAK1/JAK2/JAK3/TYK2 and Syk, respectively. Also inhibits 19 other tested kinases with IC50 less than 200 nM.

C-Fms, JAK, MLK, Hippo pathway, Syk, Tyrosine Kinases

JAK/STAT signaling, Chromatin/Epigenetic, MAPK, Stem Cells, Tyrosine Kinase/Adaptors, Angiogenesis

1369761-01-2

0.9985

C20H28ClN7O3S

482

Cl.CCS(=O)(=O)N1CCN(CC1)c1ccc(Nc2ncc(C(N)=O)c(NC3CC3)n2)cc1

-20°C

Ice Packs

Small Compound