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Ceritinib - CAS 1032900-25-6

Ceritinib - CAS 1032900-25-6

MF-0013258-01

$43.64 USD
$43.64 USD
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Product Details

  • Bioactivity

    Ceritinib (LDK378) is an ALK tyrosine kinase inhibitor (IC50=200 pM) with selective, ATP-competitive, and oral activity. Ceritinib also inhibits IGF-1R, InsR, and STK22D (IC50=8/7/23 nM) . Ceritinib has antitumor activity.

  • Target

    ALK, Serine Protease, IGF-1R

  • Related Pathways

    Tyrosine Kinase/Adaptors, Angiogenesis, Proteases/Proteasome

  • CAS Number

    1032869

  • Purity

    >99.99%

  • Molecular Formula

    C28H36ClN5O3S

  • Molecular Weight

    558.14

  • SMILES

    N(C1=C(OC(C)C)C=C(C(C)=C1)C2CCNCC2)C=3N=C(NC4=C(S(C(C)C)(=O)=O)C=CC=C4)C(Cl)=CN3

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound