Certepetide - CAS 2580154-02-3

Certepetide (CEND-1), also known as iRGD, is a bifunctional cyclic peptide that enhances tumor penetration. By interacting with alphav-integrins through its RGD motif and activating NRP-1, it transforms the solid tumor microenvironment into a temporary conduit for therapeutic agents. This property facilitates Certepetide's accumulation in tumors, making it a valuable tool in researching pancreatic cancer and other solid tumors [1] [2] [3].

Integrin, Complement System

Immunology/Inflammation, Cytoskeletal Signaling

2580154-02-3

C37H60N14O14S2

989.09

O=C1[C@]2(N(CCC2)C(=O)CNC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(C)=O)CSSC[C@@H](C(N)=O)NC(=O)[C@H](CC(O)=O)N1)[H]

-20°C

Ice Packs

Peptide