Cetagliptin - CAS 2243737-33-7

Cetagliptin is an orally active inhibitor of dipeptidyl peptidase 4 (DPP-4) and CYP2D6, with an IC50 of 6 μM. It acts as a substrate for P-glycoprotein and helps reduce GLP-1 degradation, maintaining postprandial blood glucose levels. It is used in research for type 2 diabetes.

Cytochromes P450, Proteasome, P-gp

Membrane transporter/Ion channel, Ubiquitination, Metabolism, Neuroscience, Proteases/Proteasome

2243697

C18H21F6N4O5P

518.35

P(=O)(O)(O)O.C(F)(F)(F)C=1N2C([C@@H](C)N(C(C[C@@H](CC3=C(F)C=C(F)C(F)=C3)N)=O)CC2)=CN1

-20°C

Ice Packs

Small Compound