Cetzole - CAS 3043764-86-6

Cetzole (Compound 1) acts as an inducer of ferroptosis (iron-dependent cell death) through the accumulation of ROS, leading to cell death. The compound exhibits varying half-maximal cytotoxic concentrations (CC50) against several cell lines: 2.56 μM in NCI-H522, 10.31 μM in NCI-H522 GFP-SCL7A11 #8, 2.71 μM in NCI-H522 RV-GFP, 3.07 μM in HT-1080, 14.9 μM in NARF2, and 6.28 μM in MDA-MB-231. This highlights Cetzole's potential for research in cancer therapeutics.

Ferroptosis

Apoptosis

3043672

C11H11NOS

205.28

C#CC1=NC(=CS1)C2=C(C)C(O)CC2

-20°C

Ice Packs

Small Compound