1 1

Molfinity

CGAS-IN-1 - CAS 858770-07-7

CGAS-IN-1 - CAS 858770-07-7

MF-0156892-01

$0.00 USD
$0.00 USD
Sale Sold out
Taxes included.
Size
View full details

Product Details

  • Bioactivity

    CGAS-IN-1 (compound C20), a flavonoid that acts as a Cyclic GMP-AMP Synthase (cGAS) inhibitor, demonstrates IC50 values of 2.28 μM for human cGAS and 1.44 μM for mouse cGAS. By inhibiting the abnormal activation of cGAS linked to numerous immune-mediated inflammatory diseases, cGAS-IN-1 possesses potential anti-inflammatory properties [1].

  • Target

    CGAS, Others

  • Related Pathways

    Immunology/Inflammation, Others

  • CAS Number

    858770-07-7

  • Molecular Formula

    C18H19NO8

  • Molecular Weight

    377.35

  • SMILES

    COC1=CC=C2C(OC(=O)C(CCC(=O)N(CC(O)=O)CC(O)=O)=C2C)=C1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound