CGP-74514 - CAS 190653-73-7

CGP-74514 (Compound 13) is a highly selective cyclin-dependent kinase 1 (CDK1) inhibitor (IC50=25 nM) . This compound inhibits CDK1/cyclin B complex activity, resulting in G2/M phase cell cycle arrest and induction of tumor cell apoptosis, demonstrating promising applications in bladder cancer research.

Apoptosis, CDK

Apoptosis, Cell Cycle/Checkpoint

190573

0.9854

C19H24ClN7

385.89

N(C1=C2C(N(CC)C=N2)=NC(N[C@@H]3[C@H](N)CCCC3)=N1)C4=CC(Cl)=CC=C4

-20°C

Ice Packs

Small Compound