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Molfinity

CGP52411 - CAS 145915-58-8

CGP52411 - CAS 145915-58-8

MF-0004954-01

$36.16 USD
$36.16 USD
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Product Details

  • Bioactivity

    CGP52411 is an orally active, and ATP-competitive inhibitor of EGFR (IC50: 0.3 μM) . CGP52411 blocks the toxic influx of Ca2+ ions into neuronal cells and dramatically inhibits and reverses the formation of β-amyloid Aβ42 fibril aggregates. CGP52411 can be used in studies about Alzheimer's diseases.

  • Target

    Beta Amyloid, EGFR

  • Related Pathways

    Tyrosine Kinase/Adaptors, JAK/STAT signaling, Neuroscience, Angiogenesis

  • CAS Number

    145849

  • Purity

    0.9978

  • Molecular Formula

    C20H15N3O2

  • Molecular Weight

    329.35

  • SMILES

    O=C1NC(=O)c2cc(Nc3ccccc3)c(Nc3ccccc3)cc12

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound