CGP77675 - CAS 234772-64-6

CGP77675 (ZINC1488120) is a potent and selective inhibitor of Src family kinase with IC50s of 5-20 and 40 nM for the phosphorylation of peptide substrates and autophosphorylation of purified Src. CGP77675 exhibits anticancer activity.

Bcr-Abl, Src, EGFR, VEGFR

JAK/STAT signaling, Cytoskeletal Signaling, Tyrosine Kinase/Adaptors, Angiogenesis

234772-64-6

0.9966

C26H29N5O2

443.54

NC1=C2C(=CN(C2=NC=N1)C3=CC=C(CCN4CCC(O)CC4)C=C3)C5=CC(OC)=CC=C5

-20°C

Ice Packs

Small Compound