CGRP antagonist 7 - CAS 2173508-07-9

CGRP antagonist 7 is a potent calcitonin gene-related peptide receptor (CGRP) antagonist with a Ki value of 0.029 nM. It effectively inhibits CGRP receptor-mediated cyclic adenosine monophosphate (cAMP) production, with an IC50 value of 1.5 nM. This compound is useful in migraine research.

CGRP Receptor

Neuroscience, GPCR/G Protein

2173508-07-9

C30H32FN5O3

529.61

C(CNC(=O)C1=CC(C)=C(CC=2C(=O)NN=C(C)C2)C=C1)(=O)N3[C@@H](CC[C@@H]3C(C#N)(C)C)C4=CC(F)=CC=C4

-20°C

Ice Packs

Small Compound