CGS 24592 - CAS 147923-04-4

CGS-24592 is an orally active, selective, and potent inhibitor of neutral endopeptidase 24.11 (NEP), with an IC50 value of 1.6 nmol/L. It reduces the degradation of atrial natriuretic peptide (ANP), thereby increasing plasma ANP concentration and lowering blood pressure. CGS-24592 shows potential for research in cardiovascular diseases such as hypertension and congestive heart failure.

Prolyl Endopeptidase (PREP)

Proteases/Proteasome, Metabolism

147923-04-4

C19H23N2O6P

406.37

C([C@@H](C(NCCC(O)=O)=O)NCP(=O)(O)O)C1=CC=C(C=C1)C2=CC=CC=C2

-20°C

Ice Packs

Small Compound