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Chiauranib - CAS 1256349-48-0

Chiauranib - CAS 1256349-48-0

MF-0019560-01

$57.84 USD
$57.84 USD
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Product Details

  • Bioactivity

    Chiauranib is a multi-target inhibitor against tumor angiogenesis and exhibits potent anticancer effects. Chiauranib potently inhibits the angiogenesis-related kinases (VEGFR1, VEGFR2, VEGFR3, PDGFRα and c-Kit), mitosis-related kinase Aurora B, and chronic inflammation-related kinase CSF1R, with IC50 values ranging from 1-9 nM.

  • Target

    PDGFR, VEGFR, FLT, Aurora Kinase, c-Fms, c-Kit

  • Related Pathways

    Tyrosine Kinase/Adaptors, Cell Cycle/Checkpoint, Chromatin/Epigenetic, Angiogenesis

  • CAS Number

    1256301

  • Purity

    0.9922

  • Molecular Formula

    C27H21N3O3

  • Molecular Weight

    435.47

  • SMILES

    COc1ccc2c(Oc3ccc4c(cccc4c3)C(=O)Nc3ccccc3N)ccnc2c1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound