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Molfinity

CHIR-124 - CAS 405168-58-3

CHIR-124 - CAS 405168-58-3

MF-0093420-01

$36.16 USD
$36.16 USD
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Product Details

  • Bioactivity

    CHIR-124 is an effective Chk1 inhibitor (IC50: 0.3 nM) . It has 2, 000-fold selectivity against Chk2, 500- to 5, 000-fold less activity against Cdc2 and CDK2/4.

  • Target

    Src, Chk, FLT, Apoptosis, GSK-3, PDGFR

  • Related Pathways

    Apoptosis, PI3K/Akt/mTOR signaling, Cell Cycle/Checkpoint, Angiogenesis, Tyrosine Kinase/Adaptors, Stem Cells

  • CAS Number

    405107

  • Purity

    0.9835

  • Molecular Formula

    C23H22ClN5O

  • Molecular Weight

    419.91

  • SMILES

    Clc1ccc2[nH]c(=O)c(-c3nc4ccccc4[nH]3)c(N[C@@H]3CN4CCC3CC4)c2c1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound