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Molfinity

CHIR-99021 - CAS 252917-06-9

CHIR-99021 - CAS 252917-06-9

MF-0006131-01

$36.91 USD
$23.40 USD $36.91 USD
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Product Details

  • Bioactivity

    CHIR-99021 (CT99021) is an activator of the Wnt/β-catenin signaling pathway and a GSK-3α/β inhibitor (IC50=10/6.7 nM) with selective and oral activity.CHIR-99021 induces cellular autophagy, which enhances self-renewal in mouse and human embryonic stem cells.

  • Target

    Wnt/beta-catenin, Autophagy, GSK-3

  • Related Pathways

    Cytoskeletal Signaling, PI3K/Akt/mTOR signaling, Stem Cells, Autophagy

  • CAS Number

    252917-06-9

  • Purity

    0.9929

  • Molecular Formula

    C22H18Cl2N8

  • Molecular Weight

    465.34

  • SMILES

    Cc1c[nH]c(n1)-c1cnc(NCCNc2ccc(cn2)C#N)nc1-c1ccc(Cl)cc1Cl

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound