Chlorazanil - CAS 500-42-5

Chlorazanil is a triazine-derived compound that functions as a novel, orally active, and non-toxic diuretic. Chlorazanil exerts its pharmacological effect by selectively blocking sodium and chloride ion reabsorption in the distal renal tubule, promoting diuresis and modulating electrolyte balance without inducing significant systemic toxicity, in addition, chlorazanil increases renal prostaglandin activity by increased prostaglandin synthesis, marking it as a valuable agent in renal physiology research and diuretic drug development.

Prostaglandin Receptor

Immunology/Inflammation, GPCR/G Protein

453

0.9889

C9H8ClN5

221.65

ClC1=CC=C(C=C1)NC=2N=CN=C(N2)N

-20°C

Ice Packs

Small Compound