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Chloroguanabenz acetate - CAS 2242615-97-8
Chloroguanabenz acetate - CAS 2242615-97-8
SKU:MF-0119084-01
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Product Details
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Bioactivity
Chloroguanabenz (acetate) is an antiprion agent derived from guanabenz, an α2-adrenergic receptor agonist. It inhibits prion formation in vitro in both yeast and mammalian models. Additionally, Chloroguanabenz (acetate) reduces levels of the truncated huntingtin protein derivative Htt48 in HEK293T cells and is used for studying Huntington's disease.
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Target
Adrenergic Receptor
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Related Pathways
Neuroscience, GPCR/G Protein
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CAS Number
2242510
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Molecular Formula
C10H11Cl3N4O2
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Molecular Weight
325.58
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SMILES
C(C)(O)=O.C(=N/NC(=N)N)\C1=C(Cl)C(Cl)=CC=C1Cl
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound