Molfinity

CHMFL-EGFR-202 - CAS 2089381-40-6

SKU:MF-0004975-01

$120.06 USD

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Product Details

Bioactivity
CHMFL-EGFR-202 is a potent, irreversible inhibitor of EGFR mutant kinase with IC50 values of 5.3 nM for drug-resistant mutant EGFR T790M and 8.3 nM for WT EGFR kinases.
Target
BTK, MEK, EGFR
Related Pathways
Angiogenesis, JAK/STAT signaling, MAPK, Tyrosine Kinase/Adaptors
CAS Number
2089335
Purity
0.9966
Molecular Formula
C25H24ClN7O2
Molecular Weight
489.96
SMILES
NC1=C2C(=NN(C2=NC=N1)[C@H]3CN(C(C=C)=O)CCC3)C4=CC(Cl)=C(OCC5=CC=CC=N5)C=C4
Storage Temperature
-20°C
Shipping Conditions
Ice Packs
Category
Small Compound