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CHMFL-FLT3-122 - CAS 1839150-56-9

CHMFL-FLT3-122 - CAS 1839150-56-9

SKU:MF-0038688-01

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  • Bioactivity

    CHMFL-FLT3-122 is a potent and orally available FLT3 kinase inhibitor used to treat FLT3-ITD positive acute myeloid leukemia. CHMFL-FLT3-122 significantly suppressed the tumor growth in MV4-11 cell inoculated xenograft model (50 mg/kg) without exhibiting obvious toxicity in vivo.

  • Target

    Apoptosis, FLT

  • Related Pathways

    Tyrosine Kinase/Adaptors, Apoptosis, Angiogenesis

  • CAS Number

    1839085

  • Purity

    0.9963

  • Molecular Formula

    C26H29N7O2

  • Molecular Weight

    471.55

  • SMILES

    NC1=C2C(N(N=C2C3=CC=C(OC4=CC=CC=C4)C=C3)[C@H]5CN(C(CN(C)C)=O)CCC5)=NC=N1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound