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CHMFL-PI4K-127 - CAS 2377604-81-2
CHMFL-PI4K-127 - CAS 2377604-81-2
SKU:MF-0047822-01
Regular price
$1,383.80 USD
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Sale price
$1,383.80 USD
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Product Details
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Bioactivity
CHMFL-PI4K-127 (compound 15g) is a highly selective inhibitor of PfPI4K (Plasmodium falciparum PI4K kinase) with oral activity (IC50=0.9 nM) and exhibits strong inhibitory activity against Plasmodium falciparum 3D7 (EC50=25.1 nM), demonstrating significant anti-malaria effects.
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Target
Others, PI3K, PI4K
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Related Pathways
Others, PI3K/Akt/mTOR signaling
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CAS Number
2377521
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Molecular Formula
C18H15ClN4O3S
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Molecular Weight
402.85
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SMILES
N(S(=O)(=O)C1=CC=CC=C1)C2=CC(=CN=C2Cl)C=3C=C(C(NC)=O)C=NC3
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound