Cholesteryl Hemisuccinate - CAS 1510-21-0

Cholesteryl Hemisuccinate (Cholesterol hydrogen succinate) is a highly soluble cholesterol analogue often used in polar solutions for its hepatoprotective, anticancer and tumour growth inhibiting properties. Cholesteryl Hemisuccinate inhibits the hepatotoxicity of acetaminophen and prevents AAP-induced apoptosis and necrosis in hepatocytes. Cholesteryl Hemisuccinate inhibits DNA polymerase and DNA topoisomerase, thereby inhibiting DNA replication and repair as well as cell division.

DNA/RNA Synthesis, Apoptosis, Necroptosis, Topoisomerase

Cell Cycle/Checkpoint, DNA Damage/DNA Repair, Apoptosis

1489

0.9998

C31H50O4

486.73

[H][C@@]12CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC=C2C[C@H](CC[C@]12C)OC(=O)CCC(O)=O

-20°C

Ice Packs

Small Compound