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CI-39 - CAS 2132412-25-8
CI-39 - CAS 2132412-25-8
SKU:MF-0154796-01
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Product Details
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Bioactivity
CI-39, a natural antiviral product, serves as a non-nucleoside reverse transcriptase inhibitor (NNRTI) targeting wild type HIV-1. It exhibits an effective concentration (EC50) of 3.40 μM against the virus, while its cytotoxic concentration (CC50) exceeds 30 μM. This compound notably impedes HIV-1 reverse transcriptase (RT) DNA polymerase and ribonuclease H activities[1].
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Target
Others, HIV Protease
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Related Pathways
Proteases/Proteasome, Others, Microbiology/Virology
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CAS Number
2132379
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Molecular Formula
C19H18N2O4
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Molecular Weight
338.36
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SMILES
COC(=O)c1ccccc1NC(=O)Cc1cn(OC)c2ccccc12
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Natural Product