CIA-1 hcl (452087-38-6 Free base) - CAS 1049691-47-5

CIA-1 inhibits the nuclear receptor COUP-TFII, with IC50s ranging from 1.2 μM to 7.6 μM in prostate cancer cell lines.CIA-1 inhibits the growth of a variety of prostate cancer cell lines in vitro and inhibits COUP-TFII activity to regulate its target genes.CIA-1 in vivo exhibits tumor growth inhibitory effects in a mouse model of prostate cancer xenografts. inhibitory effect on tumor growth in a xenograft mouse model of prostate cancer in vivo.

Others, Orphan Receptor, Gamma-secretase

Neuroscience, Stem Cells, Others, Proteases/Proteasome, GPCR/G Protein

1049639

0.9902

C17H20ClN3O2S

365.88

Cl.N=1C=NC(NCCC2=CC=C(OC)C(OC)=C2)=C3C=C(SC13)C

-20°C

Ice Packs

Small Compound