Ciclopirox - CAS 29342-05-0

Ciclopirox (HOE296b) exerts its action by binding to and chelating trivalent cations, such as Fe3+ and Al3+, thereby inhibiting the availability of essential co-factors for enzymes. Ciclopirox is a synthetic, broad-spectrum antifungal agent with additional antibacterial and anti-inflammatory activities. This may lead to a loss of activity of enzymes that are essential for cellular metabolism, the organization of cell wall structure and other crucial cell functions. In addition, ciclopirox exerts its anti-inflammatory activity by inhibiting 5-lipoxygenase and cyclooxygenase (COX) .

Antifungal, Autophagy, ATPase, Ferroptosis, Antibacterial

Microbiology/Virology, Apoptosis, Autophagy, Membrane transporter/Ion channel

29342-05-0

0.9978

C12H17NO2

207.27

ON1C(=CC(C)=CC1=O)C2CCCCC2

-20°C

Ice Packs

Small Compound