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Molfinity

CID 2745687 - CAS 264233-05-8

CID 2745687 - CAS 264233-05-8

MF-0012108-01

$35.41 USD
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Product Details

  • Bioactivity

    CID 2745687 is a moderately potent, concentration-dependent antagonist at human GPR35 with pIC50 = 6.70. CID 2745687 cannot effectively antagonize the agonist effects of either Zaprinast or Cromolyn disodium at rodent ortholog of GPR35 in vitro[1]. However, CID 2745687 can reverse lodoxamide-mediated anti-fibrotic effects in mice in vivo[2].

  • Target

    GPCR

  • Related Pathways

    Endocrinology/Hormones, GPCR/G Protein

  • CAS Number

    264233-05-8

  • Purity

    0.9911

  • Molecular Formula

    C17H19F2N5O2S

  • Molecular Weight

    395.43

  • SMILES

    COC(=O)c1cnn(c1C=NNC(=S)NC(C)(C)C)-c1ccc(F)cc1F

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound