CID44216842 - CAS 1222513-26-9

CID44216842 (KUC103479N-02) is a potent Cdc42-selective guanine nucleotide binding lead inhibitor. The EC50s for Cdc42 WT and Cdc42Q61L mutant are 1.0 and 1.2 μM in GTP binding assay, respectively. The EC50s for Cdc42 WT and Cdc42Q61L mutant are 0.3 and 0.5 μM in GDP binding assay, respectively. Use as a molecular probe.

Ras, CDK

GPCR/G Protein, MAPK, Cell Cycle/Checkpoint

1222513-26-9

0.9966

C22H20BrN3O3S

486.38

COc1cccc(c1)C1=NN(C(C1)c1ccc(Br)cc1)c1ccc(cc1)S(N)(=O)=O

-20°C

Ice Packs

Small Compound