CIGB-300 - CAS 1072877-99-6

CIGB-300 (P15-Tat) is an anti-casein kinase 2 (CK2) peptide that exhibits anticancer properties by disrupting the phosphorylation activity of protein kinase CK2. The compound induces apoptosis in various tumor cell lines, making it valuable for research in cancer therapy.

Apoptosis, Casein Kinase

Apoptosis, Metabolism, Stem Cells

1072877-99-6

C127H215N53O30S3

3060.6

C(C=1C=2C(NC1)=CC=CC2)[C@H]3C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N4[C@](C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC5=CN=CN5)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@]([C@@H](C)O)(C(=O)N[C@H](C(O)=O)CSSC[C@H](NC(CCNC([C@@H](NC(=O)[C@H]6N(C(=O)[C@H]7N(C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CCCNC(=N)N)NC(CN)=O)=O)CCCCN)=O)CCCCN)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCC(N)=O)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCC7)CCC6)CCC(N)=O)=O)=O)C(=O)N3)[H])(CCC4)[H]

-20°C

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Peptide