Cilastatin - CAS 82009-34-5

Cilastatin (MK0791) is a renal dehydropeptidase-I and leukotriene D4 dipeptidase inhibitor. Since the antibiotic, IMIPENEM, is hydrolyzed by dehydropeptidase-I, which resides in the brush border of the renal tubule, cilastatin is administered with imipenem to increase its effectiveness. The drug also inhibits the metabolism of leukotriene D4 to leukotriene E4.

Proteasome, Antibiotic, Antibacterial

Proteases/Proteasome, Ubiquitination, Microbiology/Virology

81970

0.9971

C16H26N2O5S

358.45

CC1(C)C[C@@H]1C(=O)N\C(=C/CCCCSC[C@H](N)C(O)=O)C(O)=O

-20°C

Ice Packs

Small Compound