Cilengitide - CAS 188968-51-6

Cilengitide (EMD 121974) is a potent integrin inhibitor for the αvβ3/5 receptor (IC50: 4.1/79 nM, in cell-free assays) with approximately 10-fold selectivity against gpIIbIIIa.

Apoptosis, PD-1/PD-L1, Integrin, Autophagy, STAT

Stem Cells, Immunology/Inflammation, Apoptosis, Cell Cycle/Checkpoint, Autophagy, JAK/STAT signaling, Cytoskeletal Signaling

188911

0.998

C27H40N8O7

588.66

CC(C)[C@@H]1N(C)C(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@H](CCCNC(N)=N)NC1=O

-20°C

Ice Packs

Peptide